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DEFINITION: A clean room (or cleanroom) is an enclosed space in which airborne particulates, contaminants, and pollutants are kept within strict limits. In industry, clean rooms are used in the manufacture and servicing of hardware such as integrated circuits (ICs) and hard drives. In biotechnology and medicine, clean rooms are used when it is necessary to ensure an environment free of bacteria, viruses, or other
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CLEAN ROOMS DEFINITION (continued):
pathogens. In addition, the temperature and humidity may be controlled. Clean room specifications for particulate matter (such as dust) are defined according to the maximum allowable particle diameter, and also according to the maximum allowable number of particles per unit volume (usually cubic meters). For non-particulate contaminants, the maximum allowable density in terms of microbes per cubic meter, or molecules per cubic meter, is specified. Four fundamental rules apply to clean rooms. First, contaminants must not be introduced into the controlled environment from the outside. Second, the
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