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E-Guide: Dedupe Dos and Don'ts – Data Deduplication Technology Best Practices
Data deduplication technology can significantly reduce the amount of disk needed to store your data backups, but things that you do in your data center can actually be working against deduplication. And there are other things that don't necessarily hurt your deduplication system, but aren't a good idea anyway.
Read this article as W. Curtis Preston explains those things you should (or shouldn't) be doing if you are performing data deduplication.